Gene-Gene Interactions in Renin-Angiotensin-Aldosterone System Contributes to End-Stage Renal Disease Susceptibility in a Han Chinese Population

Objective. In this study, we investigated whether RAAS gene single nucleotide polymorphisms (SNPs) and their interactions were associated with end-stage renal stage (ESRD). Methodology and Results. This was a case-control study for 647 ESRD cases and 644 controls. AGT (M235T (rs699) and T174M (rs476...

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Main Authors: Sui-Lung Su, Hsin-Yi Yang, Chia-Chao Wu, Herng-Sheng Lee, Yuh-Feng Lin, Chi-An Hsu, Ching-Huang Lai, Chin Lin, Sen-Yeong Kao, Kuo-Cheng Lu
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2014/169798