Cell type-specific and cross-population polygenic risk score analyses of MIR137 gene pathway in schizophrenia

Cell type-specific and cross-population polygenic risk score analyses of MIR137 gene pathway in schizophrenia

Summary: Cell type-specific pathway-based polygenic risk scores (PRSs) may better inform disease biology and improve the precision of PRS-based clinical prediction. For microRNA-137 (MIR137), a leading neuropsychiatric risk gene and a post-transcriptional master regulator, we conducted a cell type-s...

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Bibliographic Details
Main Authors: Yin Yao, Wei Guo, Siwei Zhang, Hao Yu, Hao Yan, Hanwen Zhang, Alan R. Sanders, Weihua Yue, Jubao Duan
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:iScience
Subjects:
biological sciences
genomics
Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221007537

Internet

http://www.sciencedirect.com/science/article/pii/S2589004221007537

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