The distributions of protein coding genes within chromatin domains in relation to human disease

Abstract Background Our understanding of the nuclear chromatin structure has increased hugely during the last years mainly as a consequence of the advances in chromatin conformation capture methods like Hi-C. The unprecedented resolution of genome-wide interaction maps shows functional consequences...

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Bibliographic Details
Main Authors: Enrique M. Muro, Jonas Ibn-Salem, Miguel A. Andrade-Navarro
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Epigenetics & Chromatin
Subjects:
TAD
Online Access:https://doi.org/10.1186/s13072-019-0317-2