Evolutionary history expands the range of signaling interactions in hybrid multikinase networks

Evolutionary history expands the range of signaling interactions in hybrid multikinase networks

Abstract Two-component systems (TCSs) are ubiquitous signaling pathways, typically comprising a sensory histidine kinase (HK) and a response regulator, which communicate via intermolecular kinase-to-receiver domain phosphotransfer. Hybrid HKs constitute non-canonical TCS signaling pathways, with tra...

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Bibliographic Details
Main Authors: Philippe Ortet, Sylvain Fochesato, Anne-Florence Bitbol, David E. Whitworth, David Lalaouna, Catherine Santaella, Thierry Heulin, Wafa Achouak, Mohamed Barakat
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91260-w

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https://doi.org/10.1038/s41598-021-91260-w

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