Synergistic inhibition of metastatic breast cancer by dual-chemotherapy with excipient-free rhein/DOX nanodispersions

Synergistic inhibition of metastatic breast cancer by dual-chemotherapy with excipient-free rhein/DOX nanodispersions

Abstract Background The management of metastatic cancer remains a major challenge in cancer therapy worldwide. The targeted delivery of chemotherapeutic drugs through rationally designed formulations is one potential therapeutic option. Notably, excipient-free nanodispersions that are entirely compo...

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Bibliographic Details
Main Authors: Ruoning Wang, Yujie Yang, Mengmeng Yang, Dandan Yuan, Jinyu Huang, Rui Chen, Honglan Wang, Lihong Hu, Liuqing Di, Junsong Li
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Journal of Nanobiotechnology
Subjects:
Metastatic cancer
Synergistic antiproliferative effect
Rhein (RHE) and doxorubicin (DOX)
Excipient-free nanodispersions
Online Access:http://link.springer.com/article/10.1186/s12951-020-00679-2

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http://link.springer.com/article/10.1186/s12951-020-00679-2

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