Tertiary Lymphoid Structures as a Predictive Biomarker of Response to Cancer Immunotherapies

Tertiary lymphoid structures (TLS) are ectopic lymphoid formations which are formed under long-lasting inflammatory conditions, including tumours. TLS are composed predominantly of B cells, T cells and dendritic cells, and display various levels of organisation, from locally concentrated aggregates...

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Bibliographic Details
Main Authors: Marta Trüb, Alfred Zippelius
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
TLS
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.674565/full