Antibody-mediated inhibition of Nogo-A signaling promotes neurite growth in PC-12 cells

The use of a monoclonal antibody to block the neurite outgrowth inhibitor Nogo-A has been of great interest for promoting axonal recovery as a treatment for spinal cord injury. While several cellular and non-cellular assays have been developed to quantify the bioactive effects of Nogo-A signaling, d...

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Bibliographic Details
Main Authors: Iman K Yazdi, Nima Taghipour, Sarah Hmaidan, Roberto Palomba, Shilpa Scaria, Alvaro Munoz, Timothy B Boone, Ennio Tasciotti
Format: Article
Language:English
Published: SAGE Publishing 2016-01-01
Series:Journal of Tissue Engineering
Online Access:https://doi.org/10.1177/2041731416629767