Human cytomegalovirus UL29/28 protein interacts with components of the NuRD complex which promote accumulation of immediate-early RNA.

Histone deacetylation plays a pivotal role in regulating human cytomegalovirus gene expression. In this report, we have identified candidate HDAC1-interacting proteins in the context of infection by using a method for rapid immunoisolation of an epitope-tagged protein coupled with mass spectrometry....

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Bibliographic Details
Main Authors: Scott S Terhune, Nathaniel J Moorman, Ileana M Cristea, John Paul Savaryn, Christian Cuevas-Bennett, Michael P Rout, Brian T Chait, Thomas Shenk
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2891856?pdf=render