Concise Syntheses of Trifluoromethylated Cyclic and Acyclic Analogues of cADPR

A novel trifluoromethylated analogue of cADPR, 8-CF3-cIDPDE (5) was designed and synthesized via construction of N1,N9-disubstituted hypoxanthine, trifluoromethylation and intramolecular condensation. A series of acyclic analogues of cADPR were also designed and synthesized. These compounds could be...

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Bibliographic Details
Main Authors: Lihe Zhang, Liangren Zhang, Min Dong, Jian Liu, Kehui Zhang, Zhenjun Yang, Xiangchen Huang
Format: Article
Language:English
Published: MDPI AG 2010-11-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/15/12/8689/