Interleukin 21 Receptor/Ligand Interaction Is Linked to Disease Progression in Pancreatic Cancer

Interleukin 21 Receptor/Ligand Interaction Is Linked to Disease Progression in Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC) displays a marked fibro-inflammatory microenvironment in which infiltrated immune cells fail to eliminate the tumor cells and often—rather paradoxically—promote tumor progression. Of special interest are tumor-promoting T cells that assume...

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Bibliographic Details
Main Authors: Alica Linnebacher, Philipp Mayer, Nicole Marnet, Frank Bergmann, Esther Herpel, Steffie Revia, Libo Yin, Li Liu, Thilo Hackert, Thomas Giese, Ingrid Herr, Matthias M. Gaida
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cells
Subjects:
pancreatic cancer
tumor microenvironment
IL-21
Blimp-1
Th17
invasion
Online Access:https://www.mdpi.com/2073-4409/8/9/1104

Internet

https://www.mdpi.com/2073-4409/8/9/1104

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