Nucleophilic Substitution at Tetracoordinate Phosphorus. Stereochemical Course and Mechanisms of Nucleophilic Displacement Reactions at Phosphorus in Diastereomeric <i>cis</i>- and <i>trans</i>-2-Halogeno-4-methyl-1,3,2-dioxaphosphorinan-2-thiones: Experimental and DFT Studies

Nucleophilic Substitution at Tetracoordinate Phosphorus. Stereochemical Course and Mechanisms of Nucleophilic Displacement Reactions at Phosphorus in Diastereomeric <i>cis</i>- and <i>trans</i>-2-Halogeno-4-methyl-1,3,2-dioxaphosphorinan-2-thiones: Experimental and DFT Studies

Geometrical <i>cis</i>- and <i>trans</i>- isomers of 2-chloro-, 2-bromo- and 2-fluoro-4-methyl-1,3,2-dioxaphosphorinan-2-thiones were obtained in a diastereoselective way by (a) sulfurization of corresponding cyclic P<sup>III</sup>-halogenides, (b) reaction of cyc...

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Bibliographic Details
Main Authors: Marian Mikołajczyk, Barbara Ziemnicka, Jan Krzywański, Marek Cypryk, Bartłomiej Gostyński
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Molecules
Subjects:
2-halogeno-4-methyl-1,3,2-dioxaphosphorinan-2-thiones
alkaline hydrolysis
mechanism
stereochemistry
DFT calculations
Online Access:https://www.mdpi.com/1420-3049/26/12/3655

Internet

https://www.mdpi.com/1420-3049/26/12/3655

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