The cholesterol transporter ABCG1 modulates the subcellular distribution and proteolytic processing of β-amyloid precursor protein
Although intracellular cholesterol levels are known to influence the proteolysis of β-amyloid precursor protein (APP), the effect of specific genes that regulate cholesterol metabolism on APP processing remains poorly understood. The cholesterol transporter ABCG1 facilitates cholesterol efflux to HD...
Main Authors: | Gavin H. Tansley, Braydon L. Burgess, Matt T. Bryan, Su Yuan, Hirsch-Reinshagen Veronica, Pearce Jonathan, Jeniffer Y. Chan, Wilkinson Anna, Evans Jeanette, Kathryn E. Naus, McIsaac Sean, Bromley Kelley, Song Weihong, Yang Hsui-Chiung, Wang Nan, Ronald B. DeMattos, Cheryl L. Wellington |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2007-05-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520435485 |
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