Exposure to atmospheric particulate matter enhances Th17 polarization through the aryl hydrocarbon receptor.

Lung diseases, including asthma, COPD, and other autoimmune lung pathologies are aggravated by exposure to particulate matter (PM) found in air pollution. IL-17 has been shown to exacerbate airway disease in animal models. As PM is known to contain aryl hydrocarbon receptor (AHR) ligands and the AHR...

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Bibliographic Details
Main Authors: Michael van Voorhis, Samantha Knopp, Walker Julliard, John H Fechner, Xiaoji Zhang, James J Schauer, Joshua D Mezrich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24349309/?tool=EBI