IL-10 Induces T Cell Exhaustion During Transplantation of Virus Infected Hearts

IL-10 Induces T Cell Exhaustion During Transplantation of Virus Infected Hearts

Background/Aims: Unexpected transmissions of viral pathogens during solid organ transplantation (SOT) can result in severe, life-threatening diseases in transplant recipients. Immune activation contributes to disease onset. However mechanisms balancing the immune response against transmitted viral i...

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Bibliographic Details
Main Authors: Asmae Gassa, Fu Jian, Halime Kalkavan, Vikas Duhan, Nadine Honke, Namir Shaabani, Sarah-Kim Friedrich, Sebastian Dolff, Thorsten Wahlers, Andreas Kribben, Cornelia Hardt, Philipp A. Lang, Oliver Witzke, Karl S. Lang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-03-01
Series:Cellular Physiology and Biochemistry
Subjects:
LCMV
Heart transplantation
Rejection
T cell exhaustion
IL-10
Mouse model
Online Access:http://www.karger.com/Article/FullText/443067

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http://www.karger.com/Article/FullText/443067

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