MDM2 Amplification and PI3KCA Mutation in a Case of Sclerosing Rhabdomyosarcoma

A rare sclerosing variant of rhabdomyosarcoma characterized by prominent hyalinization and pseudovascular pattern has recently been described as a subtype biologically distinct from embryonal, alveolar, and pleomorphic forms. We present cytogenetic and molecular findings as well as experimental stud...

Full description

Bibliographic Details
Main Authors: Ken Kikuchi, George R. Wettach, Christopher W. Ryan, Arthur Hung, Jody E. Hooper, Carol Beadling, Andrea Warrick, Christopher L. Corless, Susan B. Olson, Charles Keller, Atiya Mansoor
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Sarcoma
Online Access:http://dx.doi.org/10.1155/2013/520858