Transcriptional Regulation of Gene Expression by microRNAs as Endogenous Decoys of Transcription Factors

Background/Aims: MicroRNAs (miRNAs) are known to produce post-transcriptional repression of gene expression. In light of the ability of decoy oligodeocynucleotides (ODNs) to sequestrate transcription factors (TFs) and the similar double-stranded structure between decoy ODNs and miRNAs, we proposed t...

Full description

Bibliographic Details
Main Authors: Chunhui Cui, Jinlong Yu, Shuxin Huang, Huiquan Zhu, Zonghai Huang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
Online Access:http://www.karger.com/Article/FullText/362952