A novel fungal metabolite inhibits Plasmodium falciparum transmission and infection

A novel fungal metabolite inhibits Plasmodium falciparum transmission and infection

Abstract Background Malaria transmission depends on infected mosquitoes and can be controlled by transmission-blocking drugs. The recently discovered FREP1-mediated malaria transmission pathway is an excellent target to screen drugs for limiting transmission. Methods To identify candidate small mole...

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Bibliographic Details
Main Authors: Guodong Niu, Xiaohong Wang, Yue Hao, Shambhu Kandel, Guomin Niu, Raphael G. Raptis, Jun Li
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Parasites & Vectors
Subjects:
Fungal metabolites
Antimalarial agent
Malaria
Mosquito
FREP1-mediated Plasmodium transmission
Purpureocillium lilacinum
Online Access:https://doi.org/10.1186/s13071-021-04677-7

Internet

https://doi.org/10.1186/s13071-021-04677-7

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