Rules of Expansion: an Updated Consensus Operator Site for the CopR-CopY Family of Bacterial Copper Exporter System Repressors

Rules of Expansion: an Updated Consensus Operator Site for the CopR-CopY Family of Bacterial Copper Exporter System Repressors

Many Gram-positive bacteria respond to copper stress by upregulating a copper export system controlled by a copper-sensitive repressor, CopR-CopY. The previous operator sequence for this family of proteins had been identified as TACANNTGTA. Here, using several recombinant proteins and mutations in v...

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Bibliographic Details
Main Authors: Henrik O’Brien, Joseph W. Alvin, Sanjay V. Menghani, Yamil Sanchez-Rosario, Koenraad Van Doorslaer, Michael D. L. Johnson
Format: Article
Language:English
Published: American Society for Microbiology 2020-05-01
Series:mSphere
Subjects:
copper
metal
operator
operon
protein
repressor
Online Access:https://doi.org/10.1128/mSphere.00411-20

Internet

https://doi.org/10.1128/mSphere.00411-20

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