T Helper Cells Fate Mapping by Co-stimulatory Molecules and its Functions in Allograft Rejection and Tolerance

T Helper Cells Fate Mapping by Co-stimulatory Molecules and its Functions in Allograft Rejection and Tolerance

T cell differentiation is dictated by a combination of T cell receptor (TCR) interaction with an antigen-bound major histocompatibility complex (MHC), and co-stimulatory molecules signal. The co-stimulatory signal can be positive or negative, and amplifying or diminishing the initial signal. However...

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Bibliographic Details
Main Authors: R Abdoli, N Najafian
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2014-07-01
Series:International Journal of Organ Transplantation Medicine
Subjects:
T cell receptor
Receptors, Antigen, B-Cell
Major histocompatibility complex
Transplantation
Antigens, differentiation, T-lymphocyte
Transplantation tolerance
T-Lymphocytes, helper-inducer
T-Lymphocytes, regulatory
Online Access:http://www.ijotm.com/ojs/index.php/IJOTM/article/view/204

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http://www.ijotm.com/ojs/index.php/IJOTM/article/view/204

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