T Helper Cells Fate Mapping by Co-stimulatory Molecules and its Functions in Allograft Rejection and Tolerance
T cell differentiation is dictated by a combination of T cell receptor (TCR) interaction with an antigen-bound major histocompatibility complex (MHC), and co-stimulatory molecules signal. The co-stimulatory signal can be positive or negative, and amplifying or diminishing the initial signal. However...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Shiraz University of Medical Sciences
2014-07-01
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Series: | International Journal of Organ Transplantation Medicine |
Subjects: | |
Online Access: | http://www.ijotm.com/ojs/index.php/IJOTM/article/view/204 |