Wavelet Screening: a novel approach to analyzing GWAS data

Wavelet Screening: a novel approach to analyzing GWAS data

Abstract Background Traditional methods for single-variant genome-wide association study (GWAS) incur a substantial multiple-testing burden because of the need to test for associations with a vast number of single-nucleotide polymorphisms (SNPs) simultaneously. Further, by ignoring more complex join...

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Bibliographic Details
Main Authors: William R. P. Denault, Håkon K. Gjessing, Julius Juodakis, Bo Jacobsson, Astanand Jugessur
Format: Article
Language:English
Published: BMC 2021-10-01
Series:BMC Bioinformatics
Subjects:
SNP
GWAS
Multiple testing
Polygenic association
Wavelet regression
Online Access:https://doi.org/10.1186/s12859-021-04356-5

Internet

https://doi.org/10.1186/s12859-021-04356-5

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