Profiling of Mitochondrial DNA Heteroplasmy in a Prospective Oral Squamous Cell Carcinoma Study

Profiling of Mitochondrial DNA Heteroplasmy in a Prospective Oral Squamous Cell Carcinoma Study

While a shift in energy metabolism is essential to cancers, the knowledge about the involvement of the mitochondrial genome in tumorigenesis and progression in oral squamous cell carcinoma (OSCC) is still very limited. In this study, we evaluated 37 OSCC tumors and the corresponding benign mucosa ti...

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Bibliographic Details
Main Authors: Liane Fendt, Federica Fazzini, Hansi Weissensteiner, Emanuel Bruckmoser, Sebastian Schönherr, Georg Schäfer, Jamie Lee Losso, Gertraud A. Streiter, Claudia Lamina, Michael Rasse, Helmut Klocker, Barbara Kofler, Anita Kloss-Brandstätter, Christian W. Huck, Florian Kronenberg, Johannes Laimer
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cancers
Subjects:
oral cancer
oral squamous cell carcinoma
OSCC
heteroplasmy
mitochondrial DNA
mtDNA
Online Access:https://www.mdpi.com/2072-6694/12/7/1933

Internet

https://www.mdpi.com/2072-6694/12/7/1933

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