Isoforsythiaside Attenuates Alzheimer's Disease Via Regulating Mitochondrial Function Through the PI3K/AKT Pathway

Isoforsythiaside Attenuates Alzheimer's Disease Via Regulating Mitochondrial Function Through the PI3K/AKT Pathway

Improving mitochondrial dysfunction and inhibiting apoptosis has always been regarded as a treatment strategy for Alzheimer's disease (AD). Isoforsythiaside (IFY), a phenylethanoid glycoside isolated from the dried fruit of <i>Forsythia suspensa</i>, displays antioxidant activity. T...

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Bibliographic Details
Main Authors: Chunyue Wang, Jie Hao, Xin Liu, Chenliang Li, Xuyang Yuan, Robert J. Lee, Tian Bai, Di Wang
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
Alzheimer's disease
isoforsythiaside
mitochondrial apoptosis
PI3K/AKT pathway
BCL-2 family
Online Access:https://www.mdpi.com/1422-0067/21/16/5687

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https://www.mdpi.com/1422-0067/21/16/5687

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