Human neonatal cardiovascular progenitors: unlocking the secret to regenerative ability.

Although clinical benefit can be achieved after cardiac transplantation of adult c-kit+ or cardiosphere-derived cells for myocardial repair, these stem cells lack the regenerative capacity unique to neonatal cardiovascular stem cells. Unraveling the molecular basis for this age-related discrepancy i...

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Bibliographic Details
Main Authors: Tania I Fuentes, Nancy Appleby, Eric Tsay, J Julian Martinez, Leonard Bailey, Nahidh Hasaniya, Mary Kearns-Jonker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3810469?pdf=render