IL-21 promotes the development of a CD73-positive Vγ9Vδ2 T cell regulatory population

IL-21 promotes the development of a CD73-positive Vγ9Vδ2 T cell regulatory population

Vγ9Vδ2 T cells contribute to the immune response against many tumor types through their direct cytotoxic activity and capacity to regulate the biological functions of other immune cells, such as dendritic cells and IFN-γ-producing CD8+ T cells. However, their presence in the tumor microenvironment h...

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Bibliographic Details
Main Authors: Clément Barjon, Henri-Alexandre Michaud, Angeline Fages, Cécile Dejou, Alexandre Zampieri, Laetitia They, Aurélie Gennetier, Françoise Sanchez, Laurent Gros, Jean-François Eliaou, Nathalie Bonnefoy, Virginie Lafont
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:OncoImmunology
Subjects:
γδ t cells
cd73
il-10
il-21
adenosine
regulatory functions
tumor microenvironment
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1379642

Internet

http://dx.doi.org/10.1080/2162402X.2017.1379642

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