In vitro megakaryocyte differentiation and proplatelet formation in Ph-negative classical myeloproliferative neoplasms: distinct patterns in the different clinical phenotypes.

<h4>Background</h4>Ph-negative myeloproliferative neoplasms (MPNs) are clonal disorders that include primary myelofibrosis (PMF), polycythemia vera (PV) and essential thrombocythemia (ET). Although the pathogenesis of MPNs is still incompletely understood, an involvement of the megakaryo...

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Bibliographic Details
Main Authors: Alessandra Balduini, Stefania Badalucco, Maria Teresa Pugliano, Denis Baev, Annalisa De Silvestri, Marco Cattaneo, Vittorio Rosti, Giovanni Barosi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21698292/pdf/?tool=EBI