Co-delivery of Cisplatin(IV) and Capecitabine as an Effective and Non-toxic Cancer Treatment

Co-delivery of Cisplatin(IV) and Capecitabine as an Effective and Non-toxic Cancer Treatment

A strategy for preparing composite micelles (CM) containing both cisplatin(IV) [CisPt(IV)] prodrug and capecitabine using a co-assembly method is described in this study. The CM are capable of an effective release of the anticancer drug cisplatin(II) [CisPt(II)] and capecitabine via acid hydrolysis...

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Bibliographic Details
Main Authors: Xiao Xiao, Ting Wang, Leijiao Li, Zhongli Zhu, Weina Zhang, Guihua Cui, Wenliang Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Pharmacology
Subjects:
co-delivery
cisplatin(IV)
capecitabine
cancer treatment
composite micelles
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00110/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00110/full

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