Human uterine lymphocytes acquire a more experienced and tolerogenic phenotype during pregnancy

Abstract Pregnancy requires a delicate immune balance that nurtures the allogeneic fetus, while maintaining reactivity against pathogens. Despite increasing knowledge, data is lacking on the transition of pre-pregnancy endometrial lymphocytes to a pregnancy state. Here, we immunophenotyped lymphocyt...

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Bibliographic Details
Main Authors: Dorien Feyaerts, Marilen Benner, Bram van Cranenbroek, Olivier W. H. van der Heijden, Irma Joosten, Renate G. van der Molen
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-03191-0