An Expandable, Inducible Hemangioblast State Regulated by Fibroblast Growth Factor

During development, the hematopoietic and vascular lineages are thought to descend from common mesodermal progenitors called hemangioblasts. Here we identify six transcription factors, Gata2, Lmo2, Mycn, Pitx2, Sox17, and Tal1, that “trap” murine cells in a proliferative state and endow them with a...

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Bibliographic Details
Main Authors: David T. Vereide, Vernella Vickerman, Scott A. Swanson, Li-Fang Chu, Brian E. McIntosh, James A. Thomson
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671114003257