Regulation of substantia nigra pars reticulata GABAergic neuron activity by hydrogen peroxide via flufenamic acid-sensitive channels and KATP channels

Regulation of substantia nigra pars reticulata GABAergic neuron activity by hydrogen peroxide via flufenamic acid-sensitive channels and KATP channels

Substantia nigra pars reticulata (SNr) GABAergic neurons are key output neurons of the basal ganglia. Given the role of these neurons in motor control, it is important to understand factors that regulate their firing rate and pattern. One potential regulator is hydrogen peroxide (H2O2), a reactive o...

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Bibliographic Details
Main Authors: Christian R Lee, Paul eWitkovsky, Margaret E Rice
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-04-01
Series:Frontiers in Systems Neuroscience
Subjects:
Basal Ganglia
KATP Channels
Reactive Oxygen Species
Substantia Nigra
GABA
TRP channels
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnsys.2011.00014/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnsys.2011.00014/full

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