The crystal structure and small-angle X-ray analysis of CsdL/TcdA reveal a new tRNA binding motif in the MoeB/E1 superfamily.

Cyclic N6-threonylcarbamoyladenosine ('cyclic t6A', ct(6)A) is a non-thiolated hypermodification found in transfer RNAs (tRNAs) in bacteria, protists, fungi and plants. In bacteria and yeast cells ct(6)A has been shown to enhance translation fidelity and efficiency of ANN codons by improvi...

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Bibliographic Details
Main Authors: Miguel López-Estepa, Ana Ardá, Martin Savko, Adam Round, William E Shepard, Marta Bruix, Miquel Coll, Francisco J Fernández, Jesús Jiménez-Barbero, M Cristina Vega
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0118606