Development and Optimization of an ELISA to Quantitate C3(H2O) as a Marker of Human Disease

Development and Optimization of an ELISA to Quantitate C3(H2O) as a Marker of Human Disease

Discovery of a C3(H2O) uptake pathway has led to renewed interest in this alternative pathway triggering form of C3 in human biospecimens. Previously, a quantifiable method to measure C3(H2O), not confounded by other complement activation products, was unavailable. Herein, we describe a sensitive an...

Full description

Bibliographic Details
Main Authors: Michelle Elvington, M. Kathryn Liszewski, Alexis R. Liszewski, Hrishikesh S. Kulkarni, Ramsey R. Hachem, Thalachallour Mohanakumar, Alfred H. J. Kim, John P. Atkinson
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
complement
C3
human
autoimmunity
ELISA
C3(H2O)
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00703/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00703/full

Similar Items