Characterization and Pharmacokinetic Study of Aprepitant Solid Dispersions with Soluplus®

Characterization and Pharmacokinetic Study of Aprepitant Solid Dispersions with Soluplus®

Solid dispersions are a useful approach to improve the dissolution rate and bioavailability of poorly water-soluble active pharmaceutical ingredients (APIs). The aim of this study was to improve the physicochemical properties and bioavailability of a poorly water-soluble aprepitant by preparation of...

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Bibliographic Details
Main Authors: Jinwen Liu, Meijuan Zou, Hongyu Piao, Yi Liu, Bo Tang, Ying Gao, Ning Ma, Gang Cheng
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:Molecules
Subjects:
aprepitant
Soluplus®
solid dispersions
Online Access:http://www.mdpi.com/1420-3049/20/6/11345

Internet

http://www.mdpi.com/1420-3049/20/6/11345

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