TNFRSF12A and CD38 Contribute to a Vicious Circle for Chronic Obstructive Pulmonary Disease by Engaging Senescence Pathways

TNFRSF12A and CD38 Contribute to a Vicious Circle for Chronic Obstructive Pulmonary Disease by Engaging Senescence Pathways

Pathogenesis of chronic obstructive pulmonary disease (COPD) is dependent on chronic inflammation and is hypothesized to represent organ-specific senescence phenotype. Identification of senescence-associated gene drivers for the development of COPD is warranted. By employing automated pipeline, we h...

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Bibliographic Details
Main Authors: Yan Dong, Hongbao Cao, Rongyuan Cao, Ancha Baranova
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
senescence
lung
chronic inflammation
aging
tissue remodeling
network analysis
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00330/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2020.00330/full

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