Increase in Kelch 13 Polymorphisms in Plasmodium falciparum, Southern Rwanda

Increase in Kelch 13 Polymorphisms in Plasmodium falciparum, Southern Rwanda

Artemisinin resistance in Plasmodium falciparum is associated with nonsynonymous mutations in the Kelch 13 (K13) propeller domain. We found that 12.1% (8/66) of clinical P. falciparum isolates from Huye district, Rwanda, exhibited K13 mutations, including R561H, a validated resistance marker. K13 m...

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Bibliographic Details
Main Authors: Clara Bergmann, Welmoed van Loon, Felix Habarugira, Costanza Tacoli, Julia C. Jäger, Darius Savelsberg, Fabian Nshimiyimana, Elias Rwamugema, Djibril Mbarushimana, Jules Ndoli, Augustin Sendegeya, Claude Bayingana, Frank P. Mockenhaupt
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2021-01-01
Series:Emerging Infectious Diseases
Subjects:
antimicrobial resistance
artemisinin
Kelch
malaria
mutation
parasites
Online Access:https://wwwnc.cdc.gov/eid/article/27/1/20-3527_article

Internet

https://wwwnc.cdc.gov/eid/article/27/1/20-3527_article

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