Telmisartan Lowers Elevated Blood Pressure in Psoriatic Mice without Attenuating Vascular Dysfunction and Inflammation

Telmisartan Lowers Elevated Blood Pressure in Psoriatic Mice without Attenuating Vascular Dysfunction and Inflammation

Background: Psoriasis is hallmarked by vascular dysfunction, arterial hypertension, and an increased risk for cardiovascular diseases. We have shown recently that skin-driven interleukin (IL)-17A expression promotes psoriasis-like disease in mice, and this is associated with vascular inflammation, v...

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Bibliographic Details
Main Authors: Johannes Wild, Rebecca Schüler, Tanja Knopp, Michael Molitor, Sabine Kossmann, Thomas Münzel, Andreas Daiber, Ari Waisman, Philip Wenzel, Susanne Helena Karbach
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:International Journal of Molecular Sciences
Subjects:
psoriasis
vascular dysfunction and inflammation
Interleukin-17A
hypertension and anti-hypertensive treatment
telmisartan
Online Access:https://www.mdpi.com/1422-0067/20/17/4261

Internet

https://www.mdpi.com/1422-0067/20/17/4261

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