Restricting microbial exposure in early life negates the immune benefits associated with gut colonization in environments of high microbial diversity.

<h4>Background</h4>Acquisition of the intestinal microbiota in early life corresponds with the development of the mucosal immune system. Recent work on caesarean-delivered infants revealed that early microbial composition is influenced by birthing method and environment. Furthermore, we...

Full description

Bibliographic Details
Main Authors: Imke E Mulder, Bettina Schmidt, Marie Lewis, Margaret Delday, Christopher R Stokes, Mick Bailey, Rustam I Aminov, Bhupinder P Gill, John R Pluske, Claus-Dieter Mayer, Denise Kelly
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22216092/?tool=EBI