Aquaporin 4-Mediated Glutamate-Induced Astrocyte Swelling Is Partially Mediated through Metabotropic Glutamate Receptor 5 Activation

Aquaporin 4-Mediated Glutamate-Induced Astrocyte Swelling Is Partially Mediated through Metabotropic Glutamate Receptor 5 Activation

Astrocytes are one of the most abundant cell types in the mammalian central nervous system (CNS), and astrocyte swelling is the primary event associated with brain edema. Glutamate, the principal excitatory amino acid neurotransmitter in the CNS, is released at high levels after brain injury includi...

Full description

Bibliographic Details
Main Authors: Fang Yuan, Zhongfang Shi, Wei Zhang, Yang Lu, Yi Lu, Lixin Xu, Qing Fang, Min Wu, Mei Jia, Yujiao Wang, Liping Dong, Xu Yan, Shaohua Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-04-01
Series:Frontiers in Cellular Neuroscience
Subjects:
astrocyte
swelling
glutamate
aquaporin 4
metabotropic glutamate receptor 5
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2017.00116/full

Internet

http://journal.frontiersin.org/article/10.3389/fncel.2017.00116/full

Similar Items