Catalpol Increases Brain Angiogenesis and Up-Regulates VEGF and EPO in the Rat after Permanent Middle Cerebral Artery Occlusion

<p>To investigate the role and mechanism of catalpol in brain angiogenesis in a rat model of stroke, the effect of catalpol (5 mg/kg; i.p) or vehicle administered 24 hours after permanent middle cerebral artery occlusion (pMCAO) on behavior, angiogenesis, ultra-structural integrity of brain ca...

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Bibliographic Details
Main Author: Hui-Feng Zhu, Dong Wan, Yong Luo, Jia-Li Zhou, Li Chen, Xiao-Yu Xu
Format: Article
Language:English
Published: Ivyspring International Publisher 2010-01-01
Series:International Journal of Biological Sciences
Online Access:http://www.biolsci.org/v06p0443.htm