An OB-fold complex controls the repair pathways for DNA double-strand breaks

An OB-fold complex controls the repair pathways for DNA double-strand breaks

How repair pathway selection occurs is still a matter of debate and many factors have been associated to this function. Here the authors provide insight into the role of FAM35A and C20ORF196, two REV7-interacting proteins, which are recruited at double-strand breaks to promote non-homologous end joi...

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Bibliographic Details
Main Authors: Shengxian Gao, Sumin Feng, Shaokai Ning, Jingyan Liu, Huayu Zhao, Yixi Xu, Jinfeng Shang, Kejiao Li, Qing Li, Rong Guo, Dongyi Xu
Format: Article
Language:English
Published: Nature Publishing Group 2018-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06407-7

Internet

https://doi.org/10.1038/s41467-018-06407-7

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