Structures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif

Mark Ultsch et al. report X-ray and NMR structures of the N-terminal domain of two closely related innate immunity proteins, ApoL1 and ApoL2. Their findings contribute to a better understanding of the ApoL immune protein family.

Bibliographic Details
Main Authors: Mark Ultsch, Michael J. Holliday, Stefan Gerhardy, Paul Moran, Suzie J. Scales, Nidhi Gupta, Francesca Oltrabella, Cecilia Chiu, Wayne Fairbrother, Charles Eigenbrot, Daniel Kirchhofer
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02387-5