LRRK2 A419V is not associated with Parkinson's disease in different Chinese populations.

It has been suggested that a common LRRK2 polymorphic variant (A419V (rs34594498 C >T)) may be a risk factor among Asians (especially in Taiwan). In this study, we examined this variant in a larger and independent Taiwan cohort. We found the frequency of the variant (A419V) to be very rare in our...

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Main Authors: Yih Ru Wu, Louis C Tan, Xiaoli Fu, Chiung Mei Chen, Wing Lok Au, Ling Chen, Yi Chun Chen, Kumar M Prakash, Yifan Zheng, Guey-Jen Lee-Chen, Yi Zhao, Jin-Sheng Zeng, Eng King Tan, Zhong Pei
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3393727?pdf=render