The Histone Variant MacroH2A1 Regulates Key Genes for Myogenic Cell Fusion in a Splice-Isoform Dependent Manner

The Histone Variant MacroH2A1 Regulates Key Genes for Myogenic Cell Fusion in a Splice-Isoform Dependent Manner

MacroH2A histone variants have functions in differentiation, somatic cell reprogramming and cancer. However, at present, it is not clear how macroH2As affect gene regulation to exert these functions. We have parted from the initial observation that loss of total macroH2A1 led to a change in the morp...

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Bibliographic Details
Main Authors: Sarah Hurtado-Bagès, Melanija Posavec Marjanovic, Vanesa Valero, Roberto Malinverni, David Corujo, Philippe Bouvet, Anne-Claire Lavigne, Kerstin Bystricky, Marcus Buschbeck
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cells
Subjects:
histone variants
myogenic differentiation
myotubes
cell fusion
macroH2A
PARP1
Online Access:https://www.mdpi.com/2073-4409/9/5/1109

Internet

https://www.mdpi.com/2073-4409/9/5/1109

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