Computational Prediction of MoRFs, Short Disorder-to-order Transitioning Protein Binding Regions

Molecular recognition features (MoRFs) are short protein-binding regions that undergo disorder-to-order transitions (induced folding) upon binding protein partners. These regions are abundant in nature and can be predicted from protein sequences based on their distinctive sequence signatures. This f...

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Bibliographic Details
Main Authors: Akila Katuwawala, Zhenling Peng, Jianyi Yang, Lukasz Kurgan
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Computational and Structural Biotechnology Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037019300340