Gas7 knockout affects PINK1 expression and mitochondrial dynamics in mouse cortical neurons

Abstract Dynamic fission and fusion events regulate mitochondrial shape, distribution, and rejuvenation, and proper control of these processes is essential for neuronal homeostasis. Here, we report that Gas7, a known cytoskeleton regulator, controls mitochondrial dynamics within neurons of the centr...

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Bibliographic Details
Main Authors: Jagannatham Naidu Bhupana, Bo‐Tsang Huang, Gunn‐Guang Liou, Marcus J. Calkins, Sue Lin‐Chao
Format: Article
Language:English
Published: Wiley 2020-03-01
Series:FASEB BioAdvances
Subjects:
Online Access:https://doi.org/10.1096/fba.2019-00091