MEK inhibitors and their potential in the treatment of advanced melanoma: the advantages of combination therapy

MEK inhibitors and their potential in the treatment of advanced melanoma: the advantages of combination therapy

Khiem A Tran,1,* Michelle Y Cheng,1,* Anupam Mitra,1 Hiromi Ogawa,1 Vivian Y Shi,1 Laura P Olney,1 April M Kloxin,2 Emanual Maverakis1 1Department of Dermatology, University of California, Davis, Sacramento, CA, USA; 2Department of Chemical and Biomolecular Engineering, University...

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Bibliographic Details
Main Authors: Tran KA, Cheng MY, Mitra A, Ogawa H, Shi VY, Olney LP, Kloxin AM, Maverakis E
Format: Article
Language:English
Published: Dove Medical Press 2015-12-01
Series:Drug Design, Development and Therapy
Subjects:
melanoma
cobimetinib
trametinib
vemurafenib
dabrafenib
BRAF inhibitor
MEK inhibitor
MAPK pathway
Online Access:https://www.dovepress.com/mek-inhibitors-and-their-potential-in-the-treatment-of-advanced-melano-peer-reviewed-article-DDDT

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https://www.dovepress.com/mek-inhibitors-and-their-potential-in-the-treatment-of-advanced-melano-peer-reviewed-article-DDDT

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