Decreased mitochondrial DNA content in association with exposure to polycyclic aromatic hydrocarbons in house dust during wintertime: from a population enquiry to cell culture.

Polycyclic aromatic hydrocarbons (PAHs) are widespread environmental pollutants that are formed in combustion processes. At the cellular level, exposure to PAHs causes oxidative stress and/or some of it congeners bind to DNA, which may interact with mitochondrial function. However, the influence of...

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Bibliographic Details
Main Authors: Nicky Pieters, Gudrun Koppen, Karen Smeets, Dorota Napierska, Michelle Plusquin, Sofie De Prins, Hendrik Van De Weghe, Vera Nelen, Bianca Cox, Ann Cuypers, Peter Hoet, Greet Schoeters, Tim S Nawrot
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3643917?pdf=render