Pathogenic nontuberculous mycobacteria resist and inactivate cathelicidin: implication of a novel role for polar mycobacterial lipids.

Nontuberculous mycobacteria (NTM) are a large group of environmental organisms with worldwide distribution, but only a relatively few are known to be pathogenic. Chronic, debilitating lung disease is the most common manifestation of NTM infection, which is often refractory to treatment. The incidenc...

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Bibliographic Details
Main Authors: Jennifer R Honda, Tamara Hess, Kenneth C Malcolm, Alida R Ovrutsky, Xiyuan Bai, Vida R Irani, Karen M Dobos, Edward D Chan, Sonia C Flores
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4436335?pdf=render