IL-10 ameliorates TNF-α induced meniscus degeneration in mature meniscal tissue in vitro

Abstract Background Joint inflammation causes meniscus degeneration and can exacerbate post-traumatic meniscus injuries by extracellular matrix degradation, cellular de-differentiation and cell death. The aim of this study was to examine whether anti-inflammatory interleukin-10 exerts protective eff...

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Bibliographic Details
Main Authors: P. Behrendt, K. Häfelein, A. Preusse-Prange, A. Bayer, A. Seekamp, B. Kurz
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Musculoskeletal Disorders
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12891-017-1561-x