Metabolic Changes Precede the Development of Pulmonary Hypertension in the Monocrotaline Exposed Rat Lung.

There is increasing interest in the potential for metabolic profiling to evaluate the progression of pulmonary hypertension (PH). However, a detailed analysis of the metabolic changes in lungs at the early stage of PH, characterized by increased pulmonary artery pressure but prior to the development...

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Bibliographic Details
Main Authors: Olga Rafikova, Mary L Meadows, Jason M Kinchen, Robert P Mohney, Emin Maltepe, Ankit A Desai, Jason X-J Yuan, Joe G N Garcia, Jeffrey R Fineman, Ruslan Rafikov, Stephen M Black
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0150480