Critical Phenomena in the Temperature-Pressure-Crowding Phase Diagram of a Protein
Inside the cell, proteins fold and perform complex functions through global structural rearrangements. For proper function, they need to be at the brink of instability to be susceptible to small environmental fluctuations yet stable enough to maintain structural integrity. These apparently conflicti...
Main Authors: | Andrei G. Gasic, Mayank M. Boob, Maxim B. Prigozhin, Dirar Homouz, Caleb M. Daugherty, Martin Gruebele, Margaret S. Cheung |
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Format: | Article |
Language: | English |
Published: |
American Physical Society
2019-11-01
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Series: | Physical Review X |
Online Access: | http://doi.org/10.1103/PhysRevX.9.041035 |
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